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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b91f0297f94974d8bbc66b920b8621842f1dadc2f00941b853b2ce828adb67f5' 
  AND token = 'i2NJozDD3u9oEYSmDBpoeC3d1aiAsxGUPxnhmO1BvLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}