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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8298e1e8a57688201fededadcddce4aaadffe72b312e8523650d95e32aff62fa' 
  AND token = 'rxEra/MVXZJxmvn2b8C2f15SdPACtqrSGBDGWyXMsNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}