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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e796e82950091462b0e9851fa4a055645c38881059725e08f2ed1852cc1b2ab1' 
  AND token = 'PM0mPytWBcok6idHRN23Y3+dpEafxg9lpZQ9A5VcBRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}