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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '355ea0132c66d4bf9df10e2fcd687fd1b8893eaefab2c1de0fa4cf5afb1b859c' 
  AND token = 'jBRY65YmB2ccQ3/hTgAxmz4fVozDiEoSLuZUtu7nyi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}