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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57ff7d3a76c90cfbb1372cbcd0c63afde6c27e11b40a22f3b33218c53105512' 
  AND token = 'Vbo1/8YYwV/5WOR4CNVc725Ax7sSGU9oMjDGjLSNkE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}