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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bfc9b29f5d267c8249c2d5596e7be520121cd6349a5544d795b40792a166b9' 
  AND token = 'rohPzeDRv+uzAGseTFIXqjEaeQaO5pXgqxgfRQcmtJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}