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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da691b921dfda1fee7964d2ffbada0b5ae57418602461266457ace977d66a39' 
  AND token = 'FbJT2fyXJpuDVVydi8dG+TzkIhHCaW0jtJPFy/z9Xhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}