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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c7790891efd810fc607f31d87fa46b6c70e16d4cf36db75dcdea7c22bd6e7b' 
  AND token = 'W+fgUGlX6g4eAlRQeKJNPuqhqJM5YwT9pfc4C7XCmGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}