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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8e496b54d128bd4f2c33881a4cd14c9fea34c11828aca6b3c15772ce4bf6a2' 
  AND token = '3lvfQ/PZPK9xP5O0dMjQzsPrfvsfWsXYUdFvOnmHLrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}