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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131d48a940d6c06c923f444c1c63634d9348015090ceb58d5a6bc9c8704b9e38' 
  AND token = 'zRDdKD6G4w8ZkWfOCU+b5vek+paXaVHBW8A0RJixeCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}