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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14920b87828c63ed696826fa6689454bf468af0ba878adbcdd8f80d2d5b0c66' 
  AND token = 'F1zyXMtwOe9BqdfPDM0hMtPIzYyo+AsDXWHoWSIhR0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}