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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c5273d899e2aeb8cdcfc69d853f8636259883f2583addb3fd801b9a0c4c923' 
  AND token = 'BhNuk6lZ5Not4b9WfiZaQV2QGNaOM5nrSTtHogUf2TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}