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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51635597bd1015f23e9547c04d0fa5581391192e20f5c08b7afc66d1d82b3ff9' 
  AND token = 'cnAkIbAcHYLGXy6D4R/OjZA+i7Xg0kbZuCtCFPvxzTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}