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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4570e5a0f91a19a8885f5579901052eea3a4cd906dcb485cf39bc6163e11c447' 
  AND token = 'uz/yyK0QdZ7CU4bEHcEpyOyuTeF2w6ZItKUnOdWsb+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}