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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec5427db0c0ad679fded4c6028edabb7f2e9de0d65c889a0c23c3af4310af65' 
  AND token = 'y7TYrdVJhms88o0ghHE/F0fXE+BuzwoCREKBL4PrnVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}