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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22beebf5cb42e35b996b7ee3c6c11f340d33cf216ef60c8be33bcb58225e2be6' 
  AND token = 'wMx3QZWHmmePgaaYQynNylqBPwem/xM59zav3Kn9Zn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}