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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd32fa777c0cfcd383adf7346345f20b30f5b884b434594ed33d2e5bdf1d278eb' 
  AND token = 'J6mEanKP3/rR+GP0PeE3f8GhrbLubkFIunRm7ZwAy7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}