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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3fc20c54749fba9af6b26ef10729326d1eb3a0bd40c507afd031bac49a17cc' 
  AND token = 'k0gpg0ZXV0gDcoCUXGeMgkpcFtDg/C+oJIK8iPmHWZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}