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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65cade6c7f7fcb71e95c104664aa7841f63b22413fa3ebabf3768bf73dbc1583' 
  AND token = 'Ty5Trc8GbKr6zyhLthbDqPO8zSw9/PXZ6DSu6mJmGC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}