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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94d78bd8b609bbf201eb06f44a161799b3a9821da24a2bab5d12cdd22eeb3ce4' 
  AND token = 'r5JBO0/gZ+TkBB4ZHQ67zEmGZg4S10gpdClXlxr3Axw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}