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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05405eaee4723a2e5241ebe46aaac06d0106ebcb19c7a1474aee2f2bd121810' 
  AND token = 'SfcJ3ByHTU70rYo3PMwdcgvQfxfsFHiyD5JM4VNP574=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}