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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e24165bceee346578e57ada859a1789c64f5a51012d8bf7ae65cf2f49c5233' 
  AND token = 'tpPe9RplF6jzS2Ih4avdwLYuuJ1t1mmbczDc0H0O0PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}