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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed5f244b2233e8942c4082f21d7408a2b4b5da3e8e5708ea92728ea1c246c54' 
  AND token = '01iCJM2CfV4vpxVYbco0jh9kTPGikFQLTxMJX7B01I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}