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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cad4d767ecc1ad9ecd5e3f228b7acee649a68ce741e5bce8ead2e452916770' 
  AND token = 'TbvDcQfj3rporH9ZvsFNr7eCrcixIsTVv3ZwslqT+5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}