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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a147866742f4f8269aad6e84a27765e4e0d293bac5fd2255ee22602e30c1c5' 
  AND token = '4mwOSPCM0KyDeLzIagbDmvrPH2JCDxCVC/x5xeIV34I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}