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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7269370d914070d3a5b996fa696a4889f6404f735583a77510b393bcd5af06ec' 
  AND token = '8mEYl1TfTJ3OMcWiOkQ8diKE2MApH5+qNW6ATWj1rF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}