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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e74683fb2f8cce01869b430bd0cb2db96e10b615e3e15a016ce3a2b9f955c4f' 
  AND token = 'pSv4wt09MCB2FS9gQcvALPK+BNLGaR3kkgeQu5hgaP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}