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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca78cea12f5f79fd40f2e16dc1b22d91356a33c702bcfe1fa00f28a8b1a59f7' 
  AND token = 'xekT0f3Ng0wZOI6vH4p3A2U08ZAVdDBcMCTCNOLoeuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}