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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0280652248477d32c6aa499136c1ff09b6ecbb886e0c2b5f453f1efadbe89639' 
  AND token = 'gtv0wERhAqPy4/TFx2uC43qBfhoWkMsBQ4WEbnLcyZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}