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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40941bb76db08951af8936e10b9b81ed3502a4d6b1a778ca805c477479c418d6' 
  AND token = 'z723zrfcnZn8zmhkDSmpAX0HqORDKVuqbtIJenK0lL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}