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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72c84778d6a505e900d31cc86a2a007585e687f5f65b0ae5f7e1b8354d14194' 
  AND token = '7qEYM0ba0vviXhtR4dwRyvbSpgnOyoM3T2H1boDoETs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}