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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26fc741056738ffec36ae27261c6764cc8459b4649faa838e3a1f6edff1b77ad' 
  AND token = '7P2TFRpnbo/fPgFO7rCawOgGyU2eqQzuZRG2XVzIkSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}