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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca48a49f9ea4bad10300e7fb5132e39b98519ad30e6e1a4f24ece9f68b0f412' 
  AND token = 'W9KDoyPvs9zNH2Aj48mKwPScCVpd7f7jG+Doch3w4Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}