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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c620d9ec8138025244d806b35c62ead9273af58699aa75d77045e1cc85964393' 
  AND token = '1GUyR6uIUD+yySmpL7I7UgcNPaiUMmTR6pPTkRbIsF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}