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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b60851e1a019c234e8ae3fe96a04b8e317a8ed42cfc9156b0c1d0729b93335f' 
  AND token = 'rALZ6UBYkjLcSGgFaJALQ0WcHZm2dM3Pw63zaDwWSt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}