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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa307c89236ed143e82e20f0fd4bc9440df132bdff9cb2a09b21bd3dd94f145' 
  AND token = 'jbnjLGnk2x/+gMRzD8zYnaWsrhtrK+kGxR+dY4zOh/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}