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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09dd07c1d79e713f4a19daaff8719a0add0d059749acb5fd2a06032066d2f6d9' 
  AND token = 'FGndf1oliTvem012NR7BGcUkYnlVmDEKICdcFm/bG3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}