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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71bac2989bd917b10b400f8e3035b25818774f2ebc899595e7d1e3e22dd41545' 
  AND token = 'trx+nS0fyU9n3Loi5EfFg/XlFcKGxjR9ExYUG7QZjPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}