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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b7ceb1812906c2a362fa84d7a6b8b952abf17e94020e93aaddc3cfe2e013a44' 
  AND token = 'MIsSsZAl625Eiv6VVPMcy0wmSO6V2KlD2xfJxyyMcBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}