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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d4c8f17a51f3a5c597822b370bf62ce1d3e0a12337188c55f2dd017e89f110' 
  AND token = 'WbrzBX3biDKVWOyvMqz4K2OAdpvgCXo77WY2Zm2WZ+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}