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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa19b74074a8e5fb896c19b9e3d299cb1e4502fdd77edf805210d2664d293da' 
  AND token = '8SKl4RxeQmdNgb9PtmRqPMZs1c0yfFM+D8ufN6JvsIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}