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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c68d63320bc7f1bfe213b9d9da4e0746c05c967b377d7e8a518d8b00a3c670' 
  AND token = 'nSZOk7TIK0l7wF6eYHA6e7/1QJgkkaPWyKzhAgr57dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}