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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a8080e63a3beeb003e2837f6acb0d86141b689522550eac6b2c60b2a8795bd' 
  AND token = '0P0orS5s8vIU5spnIBvzCytxE25HQeoyrmg7u38X6qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}