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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a627847ab3729d64a63f8aacba59f6c6c1d0b03ce3649b0498273cb01469547' 
  AND token = '5dcCPhkedQii3NsRJpcWOUBCARgeQOk/zgiwuvmwEzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}