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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a787e3f00a7dfec4927f2c2f29e0a3bce814d017c42ba3ec7e09622151feb22' 
  AND token = '+9WqJyzA5k0VVmjAGdx2GHNui4J31X69f0lT4f2M0Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}