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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bf29bcf84f2a41ac8aa492b6b0cdf66d7096009d51bd5a15349c1431e835f2' 
  AND token = '8+QLpMg0sEQMaC2XRO7UVvr3kYUpjj68nAOxiL1QUUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}