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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3bdf31bd91e709256466f77045f7292a034f1489fb4a9b53c2975c6c61f943' 
  AND token = 'uWEztVZ5pjUWH/MXT9u9vk16tGVW3ZUEqCJkIXATUM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}