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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31e3a42b7afc5a3fa7e59405001763cc5e2f55cf525cfbd2ed71d29c062e108' 
  AND token = '6QCNuv5iZN1kHeMGwcdrWrwhq5yZNrAba1Cv5ZbSdBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}