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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aba3c9b1468d38f9a656d8fa65a3dcd1687ceb04d64d453f0f36f4607b29a5a' 
  AND token = '2rL84wPjHXK5RcarvpHIP716Ft2GWdirUzhHrBsN8Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}