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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5efa0f332349069f885f517539d0888a32b47ce3200ea2d802eb69a10a619e0' 
  AND token = 'Q8+2nPFARSyofPAQj0kUYIfsYmi+kwdZCLuOLBjCxRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}